2394 Decision Analysis in the Surgical Treatment of Familial Adenomatous Polyposis: A Dutch-Scandinavian Collaborative Study. Hans F A Vasen, Peter Duijvendijk, Charlotte Bulow, Jan Bjork, Heiki Jarvinnen, Steffen Bulow, Amsterdam, Netherlands, Copenhagen, Denmark, Helsinki, Finland, Leiden, Netherlands, Lund, Sweden

2395 Adjuvant Therapy in Colon Cancer: Results of the German Prospective, Controlled, Randomized Multicenter Trial. Karl H. Link, Ludger Staib, Hans G. Beger, Ulm, Germany

2396 Prospective Assessment of Functional Results After Proctectomy with Coloanal Anastomosis. Alessandro Fichera, Richard B. Arenas, Marco Melis, Fabrizio Michelassi, Chicago, IL

2397 Telomerase Activity of Malignant Cells Correlates with Dukes’ Stage In Colorectal Cancer. Aqeel Ghori, Bernhard Usselmann, Steve Ferryman, Ian Fraser, Alan Morris, Coventry, United Kingdom

2398 Can Laparoscopic Surgery Enhance Colorectal Cancer Spread? Xavier Bessa, Antoni Castells, Antonio M Lacy, Loreto Boix, J. Ignasi Elizalde, Laura Gargallo, Virginia Pinol, Josep M. Pique, Barcelona, Spain

2399 Ileoanal Pouch Function Is Related to Postprandial Pouch Tone. J. Steens, W.A. Bemelman, W.J.H.J. Meijerink, G. Griffioen, R.A. Hogezand, C.B.H.W. Lamers, A.A.M. Masclee, Amsterdam, Netherlands, Leiden, Netherlands¡

2453 Synthetic Peptide YY Analog Binds to a 68 kD Cell Membrane Receptor and Delivers Fluorescent Dye for Imaging and Therapeutic Treatment of Human Pancreatic Cancers. Carson D. Liu, David Kwan, Natalie Simon, David W. McFadden, Los Angeles, CA

2454 Effective Treatment of Pancreatic Tumors with Two Multimutated Herpes Simplex Oncolytic Viruses. William Jarnagin, Priscilla McAuliffe, Howard Federoff, Paul Johnson, Yuman Fong, New York, NY, Rochester, NY

2455 Herceptin Treatment - a Novel Treatment Modality in Pancreatic Cancer. Peter Buechler, Joe O. Hines, Manuela C. Buechler, Helmut Friess, Mendel M. Roth, William H. Isacoff, Howard A Reber, Bern, Switzerland, Los Angeles, CA

2456 Functional Interleukin-4 Receptor (IL-4R) and Interleukin-2 Receptor Common Gamma Chain (IL-2R-c) on Human Gastric Carcinomas: A Possible Mechanism for Cytokine Based Therapy. Richard Essner, Tung Nguyen, Young Huynh, D. Michael Rose, Dave S. B. Hoon, Santa Monica, CA

2457 The Antioxidant N-Acetylcysteine Modulates 5-Fluorouracil Activity Against Colorectal Cancer Xenografts in Nude Mice. Simon P. Bach, Sarah T. O’Dwyer, Christopher S. Potten, Alastair J.M. Watson, Liverpool, United Kingdom, Manchester, United Kingdom

2458 Tumor Suppressor Gene Therapy and COX 2 Inhibition Additively Reduces Intestinal Neoplasia. J. I. Lew, L. Vargish, R. K. Kim, Y. Guo, F. Michelassi, R. B. Arenas, Chicago, IL

2217 Nitric Oxide Production by Kupffer Cells in Obstructive Jaundiced Rats: The Effect of Internal and External Drainage. Wen Li, James Yw Lau, Danny Wh Lee, Enders Kw Ng, Angus Cw Chan, Joseph Jy Sung, Sydney Sc Chung, Hong Kong, P. R. China

2218 Bacteria Associated with Pigment May Participate in Cholesterol Gallstone Formation. Lygia Stewart, Adair L. Oesterle, Ihsan Erden, Lawrence W. Way, San Francisco, CA

2219 The Therapeutic Efficacy of Laparascopic Choleycystectomy in the Treatment of Biliary Dyskinesia. Nilesh A. Patel, Jason J. Lamb, Daniel J. Gagne, Dennis L. Fowler, Pittsburgh, PA

2220 Laparoscopic Endobiliary Stenting: A Simplified Approach to the Management of Occult Common Bile Duct Stones. Robert D. Fanelli, Keith S. Gersin, Pittsfield, MA

2221 A Comparison of Common Bile Duct Pressures Following Botulinum Toxin Injection into the Sphincter of Oddi Versus Biliary Stenting in a Canine Model. Jeffrey M. Marks, Andrew L. Bower, Marlene Goormastic, Janis L. Malycky, Jeffrey L. Ponsky, Cleveland, OH, Mayfield Height, OH

2222 Trends in the Prevalence of Cholecystectomy and the Incidence of Cancers of the Pancreas, Extrahepatic Bile Duct, and Ampulla of Vater in the United States: 1980-1996. David R. Urbach, Lee L. Swanstrom, Yashodan Khajanchee, Paul D. Hansen, Portland, OR

2223 Does a Special Interest in Laparoscopy Improve Outcome in the Treatment of Acute Cholecystitis? Liane S. Feldman, Lori E. Medeiros, Jeffrey Barkun, Harvey H. Sigman, Jacob Garzon, Gerald M. Fried, Montreal, PQ, Canada

2224 Randomized Comparison of the Clinical Course of Gasless and Conventional Laparoscopic Cholecystectomy. Jens F. Larsen, Per Ejstrud, Jrgen Ulrik Kristensen, Vivi Pedersen, Finn Redke, Flemming Svendsen, Aalborg, Denmark

2225 Hepatic Clearance Is Reduced in Patients with Clinical Hypothyroidism. Johanna M. Inkinen, Juhani A. Sand, Jorma Salmi, Vaino Turjanmaa, Pentti Vehkalahti, Isto H. Nordback, Tampere, Finland

2226 Novel Use of Hepatocyte Growth Factor in the Treatment of Inflammatory Bowel Disease. Karim Alavi, Marshall Z. Schwartz, Rajeev Prasad, Juan P. Palazzo, Philadelphia, PA, Washington, DC, Wilmington, DE

2227 Modulation of Growth Factor Expression by Nitric Oxide During Rat Colon Anastomotic Healing. David T. Efron, Daniel Most, Udaya S. Tantry, Hanping Shi, Adrian Barbul, Baltimore, MD

2228 Sensitization of Human Colon Cancer Cells to Trail-Mediated Apoptosis. Ambrosio Hernandez, Stephanie A Schwartz, Qingding Wang, B. Mark Evers, Galveston, TX

2229 Increased Expression of Membrane Type 1-Matrix Metalloprotease (MT1- MMP) Is Found as Normal Colonic Mucosa (NM) Progresses Through Adenoma and Carcinoma-In-Situ (CIS) to INVasive Carcinoma (Inv). Sandeep Malhotra, David Eisenberg, John Scholes, Rosemary Wieczorek, Peter Shamamian, Elliot Newman, New York, NY

2230 Matrix Metalloproteinase Inhibition Enhances Colonic Anastomotic Healing. Teruo Kiyama, M. Onda, A. Tokunaga, David T. Efron, Adrian Barbul, Baltimore, MD, Tokyo, Japan

2231 Attenuated Salmonella Reduces Hepatic Tumor Burden and Improves Survival in a Model of Murine Metastatic Colon Cancer. Brad A. Feltis, Timothy Sielaff, David E. Sahar, Adam Kim, Daniel Saltzman, Carol Wells, Arnold Leonard, Minneapolis, MN

2232 Pyrrolidinedithiocarbamate Enhances the p53 Independent Apoptosis Induced by 5-FU. Simon P. Bach, Sarah T. O’Dwyer, Christopher S. Potten, Alastair Jm Watson, Liverpool, United Kingdom, Manchester, United Kingdom

2233 Environmental Factors of Temperature, Humidity, Serum Accumulation, and Cell Seeding Regulate Colon Cancer Cell Adhesion in Vitro. Stephen M. Kavic, Marc D. Basson, New Haven, CT

2234 Is Combined Colectomy and Hepatectomy for Synchrounous Metastatic Colorectal Cancer More Efficient than Staged? Heidi K. Chua, Bruce G. Wolff, David M. Nagorney, Gregory G. Tsiotos, Manuel Munoz - juarez, Dirk R. Larson, Karl Sondenaa, Kansas City, MO, Mexico City, Mexico, Rochester, MN

2235 The Influence of Faecal Diversion (Hartman Procedure) on Anorectal Motility and Perception. Roman M. Herman, Piotr Walega, Tadeusz Popiela, Krakow, Poland

2236 Predicting Conversion in Laparoscopic Colorectal Surgery: A Logistic Regression Model. Tonia M. Young-Fadok, Heung W Lee, Charles H. Darby, Rochester, MN

2237 Effects of Perioperative Analgesia Technique on Recovery After Colon Surgery. Robert Shen, Muhammad Nuri, Jasleen Jasleen, Ali Tavakkolizadeh, Richard A. Steinbrook, Michael J. Zinner, Stanley W. Ashley, Edward E. Whang, Boston, MA

2238 Value of Stool Deviation in Surgery of Perianal Crohn’s Disease. Frank Makowiec, Ulrich Adam, Ulrich T. Hopt, Michael Starlinger, Rostock, Germany, Tuebingen, Germany

2239 Endoscopic Transanal Resection Provides Palliation Equivalent to Transabdominal Resection in Patients with Metastatic Rectal Adenocarcinoma. Herbert Chen, Bruce D. George, Howard S. Kaufman, Mohammad B. Malaki, Neil Mortensen, Michael G. Kettlewell, Baltimore, MD, Oxford, United Kingdom

2240 Morphological Changes of the Anal Sphincter Musculature During and After Temporary Stool Deviation. Marco A. Sailer, Martin Fein, Karl H. Fuchs, Dieter Bussen, Claudia Grun, Arnulf Thiede, Wuerzburg, Germany

2241 Long-Term Functional Results of Low Anterior Resection Following Preoperative Radiochemoterapy for Rectal Cancer. Salvatore Pucciarelli, Riccardo Marchesin, Paola Toppan, Carlo Schievano, Mario Lise, Padova, Italy

2242 Manometric Assessment of an Artificial Bowel Sphincter in 12 Patients. Guillaume Savoye, Anne Marie Leroi, Philippe Denis, Philippe

2243 Risk of Small Bowel Obstruction (SBO) Following the Pelvic Pouch Procedure (PP). Anthony R. Maclean, Robin S. McLeod, Erin D. Kennedy, Brenda O’Connor, Davin Mukraj, Helen Macrae, Zane Cohen, Toronto, ON, Canada

2244 Function, Quality of Life and Complications After Ileal Pouch-Anal Anastomosis in Patients over 70 Years of Age. Conor P. Delaney, Babak Dadvand, Victor W. Fazio, Cleveland, OH

2245 Serological Pre-Hospital Detection of Colorectal Neoplasia in a Symptomatic Cohort - the Next Step Towards a Population Screening Programme. Nicholah G. Hurst, Darren M. Williams, Michael J. Wakelam, Tariq Ismail, Birmingham, United Kingdom

2246 Multi Option Therapeutic Strategy for Hepatic Metastases of Colorectal Cancer. Harold J. Wanebo, Clarence Soderberg, Michael P. Vezeridis, Audrey Levy, Providence, RI

2247 Surgical Treatment of Distal Third Rectal Carcinoma: Oncologic Outcome Following Rectal Excision with Coloanal Anastomosis Versus Abdominal Perineal Resection. Reza A. Gamagami, Sarhang Mohammed, Arnaud Liagre, Franck Lazorthes, San Diego, CA, Toulouse, France

2248 Detection of Lymph Node Micrometastases in Esophageal Carcinoma: Pathology of Lymph Node Involvement. Marcus Feith, Hubert J. Stein, James Mueller, J. Ruediger Siewert, Munich, Germany

2249 The Immunohistochemical Similarity of Cardiac Mucosa, Intestinal Metaplasia of the Cardia, and Barrett’s Esophagus. Steve R. Demeester, Kumari S. Wickramasinghe, Reginald L. Lord, Adam Friedman, Los Angeles, CA

2250 Telomerase Activity in Barrett’s Esophagus and Esophageal Adenocarcinoma. Mark S. Diamond, Ziad Younes, Petra H. Nass, Tsung-Tseh Wu, Parviz Nikoomanesh, Mark D. Duncan, Michael D. Crowell, John W. Harmon, Baltimore, MD, Princeton, NJ

2251 Duodenogastric Reflux and Foregut Carcinogenesis: Analysis of the Duodenal Juice in the Rodent Cancer Model. Martin Fein, Karl H. Fuchs, Helga Stopper, Dominik Wittmann, Stefanie Diem, Markus Herderich, Wuerzburg, Germany

2252 Ultrastructural Characteristics of Regenerating Squamous Islands in Barrett’s Epithelium. Majid Hashemi, Cedric G. Bremner, L. Koss Kelly, Ross M. Bremner, Reginald V. Lord, Para Chandrasoma, Jorg Theisen, Otavio L. Gastal, Jeffrey H. Peters, Tom R. Demeester, Los Angeles, CA

2253 What Is the Clinical Significance of Esophageal Histology After Antireflux Surgery? Jarmo A. Salo, Tuomo K Rantanen, Judith Makinen, Pentti Sipponen, Tuula Kiviluoto, Juhani O. Ramo, Espoo, Finland, Helsinki, Finland, Vantaa, Finland

2254 Complete Fundoplication Is NOT Associated with Increased Dysphagia in Patients with Abnormal Esophageal Motility. T. Ryan Heider, Timothy M. Farrell, S. Amanda Kircher, Mark J. Koruda, Craig Colliver, Kevin E. Behrns, Chapel Hill, NC

2255 Severe Ineffective Esophageal Motility: Results of Antireflux Surgery. Dennis Blom, Bowrey J. David, Tom R. Demeester, Jeffrey H. Peters, Cedric G. Bremner, Jeffrey A. Hagen, Steve R. Demeester, Reginald V. Lord, Michael G. Wood, Saj Wajed, Christopher Streets, Peter F. Crookes, Los Angeles, CA

2256 The Utility of Preoperative Endoscopic Ultrasound Staging of Esophageal Cancer in a Surgical Practice. David J. Bowrey, Jan Johansson, Jeffrey H. Peters, Reginald V. Lord, Jeffrey A. Hagen, Steven R. Demeester, Christopher Streets, Dennis Blom, Mike Wood, Cedric G. Bremner, Tom R. Demeester, Los Angeles, CA

2257 The Myth of Dysphagia After Antireflux Surgery: Analysis of Swallowing Difficulty in Patients with GERD. Dennis Blom, David J. Bowrey, Jeffrey H. Peters, Tom R. Demeester, Peter F. Crookes, Reginald V. Lord, Michael G. Wood, Christopher Streets, Saj Wajed, Jeffrey A. Hagen, Steve R. Demeester, Cedric G. Bremner, Los Angeles, CA

2258 Laparoscopic Fundoplication for Symptomatic But Physiologic Gastroesophageal Reflux. Reginald C. W. Bell, Philip D. Hanna, Sandy Brubaker, Boulder, CO, Englewood, CO

2259 Pharyngeal pH Measurements in Patients with Laryngeal Symptoms Prior to and During Proton Pump Inhibitor Therapy. Pablo E. Omelanczuk, Thomas R. Eubanks, Santiago Horgan, Nicole Maronian, Alan Hillel, Charles E. Pope, Carlos A. Pellegrini, Chicago, IL, Seattle, WA

2260 Morbid Obesity Does NOT Predict a Poor Outcome After Laparoscopic Antireflux Surgery. Stephen S. McNatt, C. Daniel Smith, John G. Hunter, Kathy G. Galloway, Atlanta, GA

2261 Esophageal Body Function in Patients with Paraesophageal Hernia Is Similar to Those with Gastroesophageal Reflux Disease. Stephen B. Archer, C. Daniel Smith, Gene Branum, Kathy Galloway, Patrick Waring, John G Hunter, Atlanta, GA

2262 Thoracoscopic Esophagomyotomy (EM) for Achalasia. Preoperative Patterns of Acid Reflux and Long Term Followup. James W. Maher, Jeffrey Conklin, Deb Heitshusen, Iowa City, IA

2263 Prediction of Anastomotic Complications Following Oesophageal Resection Using Automated Measurement of Gastroplasty Carbon Dioxide GAP. Peter C. Roberts, Angela McLuckie, William J. Owen, Richard J Beale, Robert C Mason, London, United Kingdom

2264 Lower Esophageal Sphincter Residual Pressure Is Related to Dysphagia or Recurrent Reflux After Nissen Fundoplication. Anna Kaminski, Reginald V. Lord, Peter F. Crookes, Cedric G. Bremner, Dennis Blom, Michael G. Wood, David J. Bowrey, Saj Wajed, Rodney Mason, Steven R. Demeester, Jeffrey H. Peters, Tom R. Demeester, Los Angeles, CA

2265 Bosentan, an Endothelin Receptor Antagonist, Augments Graft Function by Reducing Graft Circulatory Impairment Following Ischemia Reperfusion. Rocco Ricciardi, Bradley K. Schaffer, Shimul A. Shah, Steven H. Quarfordt, Barbara F. Banner, Ravi S. Chari, William C. Meyers, Worcester, MA

2266 Deficient Expression of O6-Methylguanine- DNA Methyltransferase Correlates with the Prognosis of Hepatocellular Carcinoma. Shiroh Matsukura, Hiroyuki Yakushiji, Akiomi Ogawa, Michito Mori, Masao Fukuhara, Akihiro Iyama, Tohoru Ishibashi, Yusaku Nakabeppu, Mutsuo Sekiguchi, Kohoji Miyazaki, Fukuoka, Japan, Saga, Japan

2267 Hepatic Protection in E. Coli Septic Shock as Well as Hemorrhagic Shock by MMPI Inhibition. Alberto S. Santibanez-Gallerani, Annabelle Barber, George Thomas Shires, Shelly J. Williams, Peter J. Mazolewski, Jeff Avansino, Brett Murray, Shawn Davis, Yan Zhao, Las Vegas, NV

2268 The Role of Reactive Oxygen Species in Antigen Presentation by Rat Kupffer Cell. Kosei Maemura, Zhao Li Sun, Tatehiko Wada, Gregory G Bulkley, Andrew S. Klein, Baltimore, MD

2269 Selective Internal Radiation Therapy (SIRT) for the Treatment of Advanced Colorectal Liver Metastases. Richard Strawson Stubbs, Rebecca Jane Cannan, Alex William Mitchell, Wellington, New Zealand

2270 Intraoperative Ultrasound Assessment of Hepatic Radiofrequency Ablation. D.J. Scott, W.N. Young, L.M. Watumill, G.M. Lindberg, J.B. Fleming, J.F. Huth, R.V.D.R. Jeyarajah, D. B. Jones, Dallas, TX

2271 Hepatitis Serology as a Prognostic Factor in Patients with Hepatocellular Carcinoma. Syed A. Ahmad, Malcolm M Bilimoria, F Izzo, P. Delrio, P. Marra, Trent P. Baker, Geoff A. Porter, Lee M. Ellis, Jean N. Vauthey, S. Dhamotharan, Steven A. Curley, Houston, TX, Naples, Italy

2272 Three Dimensional Magnetic Resonance Technique (3D-MR) in the Preoperative Evaluation of Liver Tumours. Rune P. Sandbu, Thomas Bjerner, Hakan Ahlstrom, Ulf H Haglund, Uppsala, Sweden

2273 Isolated Pulmonary Recurrence After Resection of Colorectal Hepatic Metastases—Is Resection Indicated? Daniel M. Labow, Joseph F Buell, Atsushi Yoshida, Ralph Layman, James M. Millis, Mark Ferguson, Mitchell C Posner, Chicago, IL

2274 Laparoscopy with Laparoscopic Ultrasound (L-LUS) for Pre-Treatment Staging of Hepatocellular Carcinoma: A Prospective Study. Marco Montorsi, Roberto Santambrogio, Paolo Bianchi, Enrico Opocher, Silvia Vellini, Luigi Bonavina, Massimo Zuin, Mauro Podda, Milan, Italy

2275 Devascularization-Modified Sugiura Procedure. Does It Have Any Role in the Management of Variceal Bleeding? A Report of Long- Term Results in Chile. Jorge A. Martinez, Alfonso F. Diaz, Claudia I. Aguayo, Mario A. Caracci, Rose M. Mege, Enrique E. Waugh, Julio R. Reyes, Santiago, Chile

2276 Surgical Results in Patients with Hepatitis Virus Related Hepatocellular Carcinoma in Taiwan. Miin-Fu Chen, Wei-Chen Lee, Long-Bin Jeng, Taipei, Taiwan, ROC

2277 Resection of Hepatic Metastases in Patients Traditionally NOT Considered Resection Candidiates. Joseph F. Buell, Daniel M. Labow, Atsushi Yoshida, Ralph Layman, David C. Cronin, J. Michael Millis, Mitchell C. Posner, Chicago, IL

2278 Lipiodol/Gelfoam Chemoembolization for Control of Carcinoid Syndrome Symptoms and Octreotide Requirements. Frank J. Wessels, Scott R. Schell, Lisa E. Moffat, James G. Caridi, Irvin F. Hawkins, Edward M. Copeland, Gainesville, FL

2279 Continuous Vascular Occlusion for Hepatectomy in Both Cirrhotic and Non-Cirrhotic Patients; Outcome from a Prospective Study. Nicholas Demartimes, Adolfo Gavelli, Reza Gamagami, Claude Huguet, Monaco

2280 The Hippurate Ratio as an Indicator of Hepatic Reserve in Cirrhotics Undergoing Liver Resection. Alan W. Hemming, Juan R. Sanabria, Paul D. Greig, Steven Gallinger, Bernard Langer, Bryce R. Taylor, Katryn Furuya, Gainesville, FL, Toronto, ON, Canada

2281 Repeat Hepatic Cryotherapy for Metastatic Colorectal Cancer. Mathew H. Chung, Kenneth Ramming, Anton J. Bilchik, Century City, CA, Santa Monica, CA

2282 Subparietal Hepaticojejunal Access Loop for Intrahepatic Stones. Jake E. J. Krige, Stephen J. Beningfield, Philippus C. Bornman, John Terblanche, Cape Town, South Africa

2283 Trocar Injuries in Laparoscopic Surgery. Sunil Bhoyrul, Mark A. Vierra, Camran Nezhat, Thomas Krummel, Lawrence W. Way, San Francisco, CA, Stanford, CA

2284 Flexible Transgastric Peritoneoscopy: A Novel Approach to Diagnostic and Therapeutic Interventions in the Peritoneal Cavity. Anthony N. Kalloo, Sergey V. Kantsevoy, Vikesh K. Singh, Carolyn A. Magee, Cheryl A. Vaughn, Susan L. Hill, Apollo Group, Baltimore, MD

2285 Diagnostic Laparoscopy in Acute Appendicitis. Marc J. P. M. Govaert, Laurens Th. De Wit, Peter Van Duijvendijk, Dirk J. Gouma, Amsterdam, Netherlands

2286 The Influence of Diabetes on the Strength of Abdominal Wall Repair in the Rat. Ram M. Spira, Aviram Nissan, Efrat Levine-Blum, Ehud Ziv, Dan Seror, Hanoch Bar-On, Herbert R. Freund, Jerusalem, Israel

2287 pbx-1, a Homeodomain Protein Transcriptional Regulator Is a Marker for Early Pancreatic Ducts and a Necessary Factor in Exocrine Differentiation. Thomas S. Maldonado, Chris A. Crisera, Alan S. Kadison, Michael T. Longaker, George K. Gittes, Kansas City, MO, New York, NY

2288 Immunonutrition in Acute Experimental Pancreatitis: Omega-3 Fatty Acid Supplementation Increases Anti-Inflammatory Cytokines and Ameliorates Organ Function. Thomas Foitzik, Guido Eibl, Paul Schneider, F. A. Wenger, C. A. Jakobi, Heinz J. Buhr, Berlin, Germany

2289 Gene Therapy for Pancreatic Cancer Using Soluble VEGF Receptor. Tohru Hoshida, Makoto Sunamura, Dan G. Duda, Fuyuhiko Motoi, Masaru Onuma, Ryuzaburou Shineha, Susumu Satomi, Seiki Matsuno, Sendai, Japan

2290 26S Proteosome Inhibition Induces Apoptosis and Activation of p21Cip1-Waf-1 in Human Pancreatic Cancer. Shimul A. Shah, Michael W. Potter, Rocco Ricciardi, Kimberly K. Elbirt, Mark P. Callery, Worcester, MA

2291 Gene Therapy with HSV-Tk of Pancreatic Cancer Cell Lines: Different Responses to GCV Treatment. Eliana Greco, Paola Fogar, Daniela Basso, Annalisa Stefani, Claudio Pasquali, Mario Plebani, Sergio Pedrazzoli, Padova, Italy

2292 Increased Susceptibility of Pancreatic Acinar Cells to Hyperstimulatory Stress in DF508 Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Heterozygous Mice. Qiang Liu, Horst Fischer, William J. Welch, Hobart W Harris, Oakland, CA, San Francisco, CA

2293 Metastatic Colo-Rectal Cancer Cells Stimulate Collagen Production by Fibroblasts. Saverio Mazza, Eliana Greco, Daniela Basso, Carlo-Federico Zambon, Filippo Navaglia, Sergio Pedrazzoli, Mario Plebani, Padova, Italy

2294 Superiority of ‘Therapeutical Cocktails’ Compared To Monotherapies In The Treatment of Acute Pancreatitis. Jens Werner, Heiko Kaiser, Thobias Keck, Jan Schmidt, Martha Maria Gebhard, Christian Herfarth, Ernst Klar, Heidelberg, Germany

2295 A Real-Time Fluorescent Model of Human Pancreatic Cancer Growth, Progression, and Metastases in the Nude Mouse. Michael Bouvet, Stephanie Nardin, Meng Yang, Xiaoen Wang, Ping Giang, A. R. Moossa, Robert M. Hoffman, San Diego, CA

2296 Hypergastrinemia Induced by Proton Pump Inhibitor (PPI) Causes Pancreatic Growth But Does NOT Promote Pancreatic Carcinogenesis. Mc Donald M. Jerome, Daniel S. Longnecker, Ravi Moonka, Linda Robinson, Richard H. Bell, Lebanon, NH, Seattle, WA, Tacoma, WA

2297 19FNMR Spectroscopic Detection and Kinetics of Conversion of 5-FC to 5-FU in Human Colon Cancer in Vivo and in Vitro: A Novel Approach for Detecting Adenoviral Cytosine Deaminase Gene Transfer. Allen N. Gustin, Pal Kiss, Gabriel A. Elgavish, Laszlo Lenard, Donald J. Buchsbaum, Selwyn M. Vickers, Birmingham, AL

2298 Effect of Low-Dose Radiation on the Expression of Intercellular Adhesion Molecule-1 and on the Leukocyte Adherence in Healthy Pancreas and in Pancreatic Carcinoma of the Rat. Eduard Ryschich, Jan Schmidt, Wolfgang Harms, Jens Werner, Sasa- Marcel Maksan, Martha Maria Gebhard, Christian Herfarth, Ernst Klar, Heidelberg, Germany

2299 Caspase 1 Overexpression in Chronic Pancreatitis Due to Ductular Proliferation. Marco Ramadani, Yinmo Yang, Frank Gansauge, Hans G. Beger, Susanne Gansauge, Beijing, P. R. China, Ulm, Germany

2300 Anti-Angiogenesis Effect of P53-Target Gene, BAI1 on Pancreatic Cancer. Makoto Sunamura, Dan G. Duda, Lucian Lozonschi, Tadamichi Yokoyama, Toshimasa Yatsuoka, Fuyuhiko Motoi, Hiromune Shimamura, Kazunori Takeda, Seiki Matsuno, Sendai, Mi, Japan

2301 Parathyroid Hormone-Related Protein Expression in Human Pancreatic Adenocarcinoma. Michael Bouvet, Stephanie R. Nardin, Douglas W. Burton, Cynthia Behling, John M. Carethers, Robert M Hoffman, A. R. Moossa, Leonard J. Deftos, San Diego, CA

2302 Gabexate Mesilate Promotes Neutrophil Apoptosis and Attenuates Serum Cytokines Alterations in Human Acute Pancreatitis. Han-Ming Chen, Miin-Fu Chen, Tsann-Long Hwang, Yi-Yin Jan, Ji- Chan Chen, Taipei, Taiwan

2303 Simultaneous Kidney-Pancreas Transplantation with Enteric Exocrine Drainage: A Prospective Comparison of Systemic Versus Portal Venous Delivery of Insulin. Robert J. Stratta, Mohammed H. Shokouh-Amiri, Hani P. Grewal, Maria F. Egidi, Tarik A. Kizilisik, Lillian W. Gaber, Ahmed O. Gaber, Memphis, TN

2304 Differences in Diagnostic Work-Up for Pancreatic Carcinoma Between Centres and General Hospitals. Esther H B M Tilleman, Tiny Benraadt, Dirk J. Gouma, Amsterdam, Netherlands

2305 Impact of Preservation of the Gastroduodenal Transit on Gastrointestinal Hormones After Surgery for Chronic Pancreatitis. Christian Bloechle, Tammo V. Schrenck, Andreas De Weerth, Timm Strotmann, Jakob R. Izbicki, Hamburg, Germany

2306 Intra-Arterial Calcium Injection (IACI)Test as Localizing Procedure in Insulinomas. Claudio Pasquali, Diego Miotto, Cosimo Sperti, Francesco Meduri, Saula De Kreutzenberg, Sergio Pedrazzoli, Padova, Italy

2307 Renal Cell Carcinoma Metastatic to the Pancreas: Results of Surgical Management. Taylor A Sohn, Charles J. Yeo, John L. Cameron, Attila Nakeeb, Keith D. Lillemoe, Baltimore, MD, Milwaukee, WI

2308 Preoperative Endoscopic Ultrasound in Pancreatic Malignancy. Frank Makowiec, Alexander Pietsch, Albrecht Holle, Hartwig Riediger, Ulrich Adam, Stefan Liebe, Ulrich T. Hopt, Rostock, Germany

2309 Outcome of Acute Pancreatitis: 41 Years of Management at a University Hospital. Archana Ramaswamy, Rea A. Brown, Lawrence Rosenberg, Montreal, PQ, Canada

2310 Determinants of Survival After Surgery for Pancreatic Necrosis Complicating Acute Pancreatitis. Garth C Beattie, James J. Powell, David Swan, Krishnakumar Madhavan, Ajith K. Siriwardena, Edinburgh, United Kingdom

2311 Mortality from Necrotizing Pancreatitis: Which Patients Die Today? Christophe A. Mueller, Beat Gloor, Waldemar Uhl, Mathias Worni, Stefan W. Schmid, Markus W. Buechler, Bern, Switzerland

2312 Laparoscopic Transduodenal Sphincteroplasty of the Minor Papilla. Dennis L. Fowler, Nancy J. Hogle, Pittsburgh, PA

2313 Does Chemoradiation Downstage Locally Advanced Pancreatic Cancer? Hong Jin Kim, Karen Czischke, Murray F Brennan, Kevin Conlon, New York, NY

2314 Hyperamylasemia in Neurosurgical Patients. Katherine J. M. Liu, Mary Jo Atten, Debra Hawkins, Evageline Panizales, Moon Ja Cho, Terry Lichtor, James Stone, Philip E. Donahue, Chicago, IL

2315 Re-Admissions After Pylorus Preserving Pancreatoduodenectomy. Rutger C. I. Geenen, Laurens Th. Wit, Thomas M. Gulik, Huug Obertop, Dirk J. Gouma, Amsterdam, Netherlands

2316 Pain Management of Patients with Unresectable Periampullary Carcinoma. Rutger C. I. Geenen, Claudia M. G. Dekker, Gertjan Tienhoven, Huug Obertop, Dirk J. Gouma, Amsterdam, Netherlands

2317 Evaluation of a New Strategy for Treatment of Severe Acute Pancreatitis. Yoshifumi Takeyama, Takashi Ueda, Yuichi Hori, Kozo Takase, Yoshikazu Kuroda, Kobe, Japan

2318 Impairment of Mucosal Immunity by Parenteral Nutrition: Decreased Nasotracheal Influenza-Specific Secretory IgA Levels and Transport in Parenterally Fed Mice. Kathryn B. Renegar, Kenneth Allan Kudsk, R. Chance Dewitt, Yong Wu, Brock K. King, Memphis, TN

2319 Preservation of the Peptide YY-Activated Ileal Brake After Proctocolectomy and Jejunal Pouch-Distal Rectal Anastomosis. Fabio V. Teixeira, Miguel Pera, Keith A. Kelly, Scottsdale, AZ

2320 Abnormal Absorptive Function of the Small Bowel Following Ischemia-Reperfusion Injury: Protection Afforded by Pyruvate. Luca Cicalese, Melissa Brown, Pierpaolo Sileri, Sergio Morini, Veronica Zuber, Jackie Blanchard, Cristiana Rastellini, Enrico Benedetti, Chicago, IL

2321 Stasis Is Associated with Ileal J-Pouch Inflammation and Oxidative Stress in a Rat Model of Ileal Pouch-Anal Anastomosis (IPAA). Khaled O Shebani, Arthur F. Stucchi, James P. McClung, Eve R. Beer, Wayne W. Lamorte, James M. Becker, Boston, MA

2322 Effect of Isografting of the Middle 50% of the Small Intestine on Luminal Transit. Gordon L. Telford, Susan Walgenbach-Telford, Gail Hilton, Hahn Pham, Walter J. Mariah, Christopher P. Johnson, Milwaukee, WI

2323 Neutral Red-Doped Albumin as a New Sealant for Intestinal Laser Soldering. Carson D. Liu, Mike Case, David W. McFadden, David Kwan, Marcos Paiva, Romaine E. Saxton, Los Angeles, CA

2324 Laparoscopic Surgery for Crohn’s Disease: Reasons for Conversion. Max Schmidt, Mark A Talamini, Howard S. Kaufman, Robert C. Moesinger, Theodore M. Bayless, Baltimore, MD

2325 Results of the Duodenal Switch for the Surgical Treatment of Morbid Obesity. Gary J. Anthone, Los Angeles, CA

2326 Successful Intestinal Transplantation: Surgical and Immunological Considerations. Menahem Ben-Haim, Thomas M. Fishbein, Thomas Schiano, Sukru Emre, Marcelo Facciuto, Patricia A. Sheiner, Myron E. Schwartz, Charles M. Miller, New York, NY

2327 Cardiopulmonary Bypass, Mesenteric Perfusion, & Small Intestinal Epithelial Integrity: Preliminary Analysis Using a Novel Protein Marker. James H. Holmes, Joshua M. Lieberman, William H. Marks, Charles B. Probert, Mark E. Hill, Daniel L. Paull, Steven W. Guyton, James Sacchettini, R. Alan Hall, College Station, TX, Seattle, WA

2328 Reduced Expression of VEGF and Its Receptors in Portal Hypertensive Gastric Mucosa Following Alcohol Injury - a Key to Impaired Angiogenesis? H. Kawanaka, M. Tomikawa, M. K. Jones, R. Pai, I. L. Szabo, K. Sugimachi, A. S. Tarnawski, I. James Sarfeh, Fukuoka, Japan, Irvine, CA, Long Beach, CA

2329 KW5139 (Synthesized 13-Leu-Motilin) Ameliorate Postoperative Gastric Stasis Caused by Hypogastroduodenal and Hyperpyloric Motility at Early After Abdominal Surgery. Koji Nakada, Nobuyoshi Hanyu, Teruaki Aoki, Tokyo, Japan

2330 Selective Role of Vagal and Non-Vagal Innervation in Control of Migrating Motor Complex (MMC) and Postprandial Motility. Toshiyuki Tanaka, Luke H. Vanklompenberg, Michael G. Sarr, Rochester, MN

2331 Peritoneal Fluid Cytology Predicts Outcome in Locally Advanced Gastric Cancer. Martin R. Weiser, Patricia Saigo, Murray F. Brennan, Martin S. Karpeh, New York, NY

2332 Laparoscopic, Open and Handport-Assisted Laparoscopic Roux-En-Y Gastric Bypass - a Comparative Study. Sven Os Gustavsson, Magnus Sundbom, Agneta Westling, Uppsala, Sweden

2333 Comparison of Postoperative Results Between Pylorus-Preserving Gastrectomy and Conventional Distal Gastrectomy for Early Gastric Cancer: A Prospective Randomized Study. Iwao Sasaki, Ken-Ichi Shiiba, Hiroo Naito, Yuji Funayama, Sei-Ichi Ishii, Tsuneo Shiratori, Akio Ohuchi, Yoshikazu Asino, Yoshinobu Takahashi, Koumei Fujiya, Akihiro Iwatsuki, Seiki Matsuno, Sendai, Japan

2334 Helicobacter Pylori in Operatively Managed Nonvariceal Acute Upper Gastrointestinal Bleeding. Christopher S. Callicutt, Stephen W. Behrman, A. Osama Gaber, Memphis, TN

2335 Risks/Benefits of Gastric Bypass in Morbidly Obese Patients with Severe Venous Stasis Disease. Harvey J. Sugerman, Elizabeth L. Sugerman, Luke Wolfe, John M. Kellum, Michael A. Schweitzer, Eric J. Demaria, Richmond, VA

2336 A Comparison of Hand-Assisted, Laparoscopic and Open Roux-En-Y Gastric Bypass Surgery. Bradley J. Needleman, Charles H. Cook, Lawrence J. Damore, E. Christopher Ellison, E. Domiguez, W. S. Melvin, Columbus, OH

2337 Gastrointestinal Leaks Following Laparoscopic Gastric Bypass (LGBP). Philip R. Schauer, Sayeed Ikramuddin, Higa, Pittsburgh, PA

2338 Quality of Life Following Laparoscopic Gastric Banding in Patients with Morbid Obesity. Stephan M. Freys, Harald Tigges, Johannes Heimbucher, Karl H. Fuchs, Martin Fein, Arnulf Thiede, Wuerzburg, Germany